Setting Expectations
The following checklist may help with setting patient expectations.
Repigmentation Develops Best in the Hair-bearing Regions.
REPIGMENT FAST
Areas with a higher density of hair follicles respond more rapidly to treatment.
Face
Arms
Legs
Torso
REPIGMENT SLOWLY
Areas with lower density respond more slowly.
M Back of hands & fingers
Feet & toes
MAY NOT REPIGMENT
Areas where hair follicles are absent or in low density.
Palms
Soles
Repigmentation May Occur in One of Multiple Patterns, Including:
Perifollicular
The most common pattern is the perifollicular pattern, which appears as small, round, repigmented areas around the hair follicles.
Marginal
The marginal pattern appears as a repigmented rim at the lesion borders.
Combined
Involves multiple patterns, such as marginal and perifollicular.
References:
- 3.Lumirix® Prescribing Information for Hong Kong.
- 8. Birlea SA, Goldstein NB, Norris DA. Repigmentation through melanocyte regeneration in vitiligo. Dermatologic clinics. 2017 Apr 1;35(2):205-18.
- 10. Rosmarin D, Sebastian M, Amster M, et al. Facial and total vitiligo area scoring index response shift during 104 weeks of Ruxolitinib cream treatment for vitiligo: results from the open-label arm of the TRuE-V long-term extension phase 3 study. Presented at the American Academy of Dermatology Annual Meeting; March 17–21, 2023; New Orleans, LA.
- 12. Harris JE, Papp K, Forman SB, et al. Relapse and maintenance of clinical response in the randomized withdrawal arm of the TRuE-V long-term extension phase 3 study of ruxolitinib cream in vitiligo. Presented at the American Academy of Dermatology Annual Meeting; March 17–21, 2023; New Orleans, LA.
- 13. Yang K, Xiong X, Pallavi G, Ling Y, Ding F, Duan W, Sun W, Ding G, Gong Q, Zhu W, Lu Y. The early repigmentation pattern of vitiligo is related to the source of melanocytes and by the choice of therapy: a retrospective cohort study. International Journal of Dermatology. 2018 Mar;57(3):324-31.
